Test Overview
Test Methodology

UPLC-MS/MS (Ultra pressure liquid chromatography tandem mass spectrometry)

Test Usage

Monitoring compliance with buprenorphine therapy and identification of specimen adulteration intended to mimic compliance with prescribed buprenorphine.

Reference Range *

Negative

Positive results for buprenorphine and/or metabolites concentration are reported quantitatively. The concentration value must be greater than or equal to the cutoff to be reported as positive.

Cutoff Concentration:
Buprenorphine: 5 ng/mL
Norbuprenorphine: 5 ng/mL
Buprenorphine Glucuronide: 5 ng/mL
Norbuprenorphine Glucuronide: 5 ng/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Mondays and Thursdays
Analytic Time

1-4 hours

Soft Order Code
UBUPM
MiChart Code
UBUPM
Synonyms
  • Buprenex
  • Butrans
  • Belbuca
  • Suboxone
  • Subutex
  • Sublocade
  • Zubsolv
  • Norbuprenorphine
  • Buprenorphine Glucuronide
Laboratory
Chemical Pathology
Section
Drug Analysis
Specimen Requirements
Collection Instructions

Collect random urine specimen in clean plastic container.

Normal Volume
3 mL random urine
Minimum Volume
1 mL random urine
Billing
CPT Code
80348 (Alt code: G0480)
Fee Code
KA031
LOINC
49752-9, 49751-1
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