Test Overview
Test Methodology

Chemiluminescent Immunoassay

Test Usage

For detection of IgG and IgM antibodies to Borrelia burgdorferi. If clinical symptoms are present, a positive test result supports the diagnosis of Lyme Disease.

Reference Range *


* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

A positive test result in the absence of clinical symptoms may be due to cross-reactivity with antibodies to non-pathogenic treponemes, infectious mononucleosis and from auto-immune disease.

Test Details
Days Set Up
Monday - Friday
Analytic Time

8 hours

Soft Order Code
MiChart Code
Borrelia (Lyme Disease) Anitbody, Serum
  • Index, Lyme disease
  • Antibody, Borrelia
  • Antibody, Lyme Disease
  • Lyme Disease Antibody
  • Borrelia burgdorferi Antibody
  • Borrelia Screen (Lyme Dis)
  • Lyme Disease Index
  • BORR
  • Tick Borne Disease
Chemical Pathology
Special Chemistry
Specimen Requirements
Collection Instructions

Collect specimen in an SST (preferred) or red top tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Normal Volume
1 mL serum
Minimum Volume
0.3 mL serum
Additional Information

Any specimen that gives a positive or eqivocal result for the Borrelia burgdorferi test will be forwarded to the Michigan Department of Health & Human Services (MDHHS) for Lyme Disease confirmatory testing at an additional charge (although there is no charge for testing, MLabs charges a handling fee for processing and forwarding specimens to MDHHS). By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. If the patient is diagnosed with Lyme disease and the immunoassay result is negative, it is recommended that a repeat specimen be sent in 6 weeks.

CPT Code
Fee Code