Borrelia burgdorfei Antibody, Spinal Fluid
BORRELIA ANTIBODY, CSF (LYME)
Lyme Disease Antibody, CSF
Tick Borne Disease
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Enzyme-Linked Immunosorbent Assay (ELISA)
Aid in the diagnosis of neuroinvasive Lyme disease or neuroborreliosis due to infection with Lyme disease associated Borrelia species (eg, B. burgdorferi, B. garinii, B. afzelli). The Lyme Antibody Index assay is designed to differentiate between true intrathecal synthesis of antibodies to Borrelia burgdorferi sensu lato (Bbsl) genospecies (e.g., B. burgdorferi, B. garinii and B. afzelii) versus the presence of anti-Bbsl antibodies in CSF due to permeability of the blood-brain barrier or as a result of a traumatic lumbar puncture.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect CSF specimen in sterile tube or container. Send CSF specimen refrigerated (preferred) or frozen in a screw-capped plastic vial. Label as spinal fluid or CSF. Collect blood specimen in an SST tube within 24 hours of the CSF specimen, preferably at the same time. Centrifuge, aliquot serum into a plastic vial and refrigerate (preferred) or freeze. Label as serum. Band CSF and serum specimens together.