Test Overview
Test Methodology

Electrochemiluminescence Immunoassay

Test Usage

Aid in monitoring response to antiresorptive therapies (e.g., bisphosphonates, hormone replacement therapy) in postmenopausal women and individuals with osteoporosis. An adjunct in diagnosis of medical conditions associated with increased bone turnover..

Reference Range *

Males
<18 years: Reference Range Not Provided
18-30 years: 120-946 pg/mL
31-50 years: 93-630 pg/mL
51-70 years: 35-836 pg/mL
>70 years: not established
Females
<18 years: Reference Range Not Provided
>18 years: Premenopausal: 25-573 pg/mL
Postmenopausal: 104-1008 pg/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Test is performed on Mondays, Wednesdays and Fridays
Analytic Time

1 Day

Soft Order Code
BCTX
MiChart Code
BCTX
Synonyms
  • C-terminal collagen crosslinks
  • B-CTx
  • C-Telopeptides, Serum
  • C-Telopeptide, Beta Cross-Linked, Serum
  • NTx-Telopeptide replacement assay
Laboratory
Chemical Pathology
Section
Automation
Specimen Requirements
Collection

Serum should be separated from cells within 2 hours of collection and frozen, if unable to analyze immediately.

Collection Instructions

Collect specimen in a red top from a fasting patient. Centrifuge and aliquot into a plastic tube and freeze. Fasting morning collection (before 10am) is recommended as diurnal variations can cause elevated levels at night. Dietary supplements containing biotin may interfere with this assay. For patients on daily supplements containing biotin (vitamin B7), or multivitamins, specimen should not be drawn until at least 8 hours after last administration.

Alternate Specimen
Yellow top
Fasting Specimen
12 hour fasting required. Specimen should be collected prior to 10 am
Normal Volume
1.0 mL Serum
Minimum Volume
0.5 mL Serum
Billing
CPT Code
82523
Fee Code
JA049
LOINC
41171-0