Test Overview
Test Methodology

Spectrophotometry/absorbance based enzyme-coupled kinetic reaction.

Test Usage

Used to monitor Asparaginase therapy for sufficient enzyme activity, to assess silent inactivation by patient sensitization. Only experienced physicians treating patients with asparaginase should interpret whether the asparaginase activiy level is adequate. There are no established treatment guidelines. The decision to modify the asparaginase treatment to achieve a target level must be made by the physician.

Test Details
Days Set Up
Monday - Friday
Analytic Time

3 - 7 days

Soft Order Code
  • L-asparaginase Assay for Leukemia Patients
Reference Laboratory
Granger Genetics
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top or SST tube. Allow to clot at room temperature for 30 minutes, but no longer than 60 minutes. Centrifuge, aliquot serum to a plastic screw capped leakproof tube, and freeze within 2 hours of collection.

Special Handling

Ship Monday through Thursday only. Store samples drawn on Friday frozen until Monday for shipment. Select the drug the patient is being administered on the Granger requisition.

Normal Volume
2 mL serum
Minimum Volume
0.5 mL serum
Storage Temperature
Frozen preferred. Refrigerated stable for only 3 days.
Additional Information

Test sent to Granger Genetics.

CPT Code
82657 x2
Fee Code
AA446 x2