Spectrophotometry/absorbance based enzyme-coupled kinetic reaction.
Used to monitor Asparaginase therapy for sufficient enzyme activity, to assess silent inactivation by patient sensitization. Only experienced physicians treating patients with asparaginase should interpret whether the asparaginase activiy level is adequate. There are no established treatment guidelines. The decision to modify the asparaginase treatment to achieve a target level must be made by the physician.
3 - 7 days
- L-asparaginase Assay for Leukemia Patients
Collect specimen in a red top or SST tube. Allow to clot at room temperature for 30 minutes, but no longer than 60 minutes. Centrifuge, aliquot serum to a plastic screw capped leakproof tube, and freeze within 2 hours of collection.
Test sent to Granger Genetics.