Days Set Up
Analytic Time

9 - 16 days

MiChart Code
Arylsulfatase A, Urine
Soft Order Code

Test Updated:


Metachromatic Leukodystrophy
Mucolipidoses, Types II and III

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Test Overview

Test Methodology

Colorimetric, Kinetic

Test Usage

Confirmation of Metachromatic Leukodystrophy. The leukocyte assay is the preferred test to order first to rule out Metachromatic Leukodystrophy. The urine assay should be used in confirming leukocyte results.

Reference Range

> or =19 nmol/h/mL. Greatly reduced levels of arylsulfatase A in urine (< or =15 nmol/h/mL), as well as in serum and various tissues, is seen in patients with metachromatic leukodystrophy.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Instructions

Collect 24 hour urine specimen with no preservative; refrigerate during collection. Aliquot 6 ml into a plastic urine container and refrigerate. Record total 24 hour urine volume and collection dates/times on request form.

24-hour Urine Jug
Normal Volume
6 ml aliquot of 24 hour urine collection
Minimum Volume
2.5 ml aliquot of 24 hour urine collection

Billing Information

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.