Test Overview
Test Methodology

Colorimetric, Kinetic

Test Usage

Confirmation of Metachromatic Leukodystrophy. The leukocyte assay is the preferred test to order first to rule out Metachromatic Leukodystrophy. The urine assay should be used in confirming leukocyte results.

Reference Range *

> or =19 nmol/h/mL. Greatly reduced levels of arylsulfatase A in urine (< or =15 nmol/h/mL), as well as in serum and various tissues, is seen in patients with metachromatic leukodystrophy.

Test Limitations

Results from this assay may not reflect carrier status because of individual variation of arylsulfatase A enzyme levels.

Test Details
Days Set Up
Friday
Analytic Time

9 - 16 days

Soft Order Code
ARSU
MiChart Code
Arylsulfatase A, Urine
Synonyms
  • Metachromatic Leukodystrophy
  • Mucolipidoses, Types II and III
  • ARSU
  • ARYLSULFATASE A, URINE
Laboratory
Sendout
Reference Laboratory
Mayo ARSU (8777)
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect 24 hour urine specimen with no preservative; refrigerate during collection. Aliquot 6 ml into a plastic urine container and refrigerate. Record total 24 hour urine volume and collection dates/times on request form.

Normal Volume
6 ml aliquot of 24 hour urine collection
Minimum Volume
2.5 ml aliquot of 24 hour urine collection
Additional Information

Test sent to Mayo Medical Laboratories.

Billing
CPT Code
84311
Fee Code
20058