Test Overview
A PCR-based assay, which includes HhaI digestion of the amplified product, is utilized to identify the 3 most common apolipoprotein E alleles (e2, e3, e4).
Determining the specific apolipoprotein E (APOE) genotypes in patients with type III hyperlipoproteinemia.
Interpretive report provided. This test detects the Apo E2, E3, and E4 genes.
This assay will not detect all of the mutations that cause type III hyperlipoproteinemia. Therefore, the absence of a detectable mutation does not rule out the possibility that an individual is a carrier of or affected with this disease. This assay cannot predict or rule out the development of Alzheimer disease in an individual. Rare polymorphisms exist that could lead to false-negative or false-positive results. If results obtained do not match the clinical findings, additional testing should be considered.
Test Details
5 - 10 days
- Apo E Genotyping
- Apolipoprotein E Genotyping by DNA Analysis
- Apo E2 Gene Detection
- Apo E3 Gene Detection
- Apo E4 Gene Detection
- APOLIPOPROTEIN E GENOTYPE PCR
- APOES
- APOE
- Apolipoprotein E Genotyping
- MLABEL
Specimen Requirements
Collect blood in a lavender top tube. Refrigerate and send intact blood within 48 hours of collection.
Additional Information
Test sent to Mayo Medical Laboratories. Specimens sent for Alzheimer's risk assessment are referred to Athena Diagnostics. The Apo E4 allele has been associated with an increased risk for late onset Alzheimer's dementia.