Evaluate abnormalities in lipoprotein fractions, assess risk for developing coronary heart disease (CHD).
Males: greater than 105 mg/dl (1.05 g/l), Females: greater than 110 mg/dl (1.1 g/l)
- Apo A-1
- APOLIPOPROTEIN A-1
Collect specimen in SST tube after an overnight (12 hours) fast . Centrifuge, aliquot serum into a plastic vial and refrigerate.
Apolipoprotein A-1 is the major protein component of high density lipoprotein (HDL). Several studies have demonstrated that patients with angiographically proven coronary artery disease have lower levels of Apo A-1 than normal individuals. Thus, Apo A-1 can be thought of as a `negative risk factor' for CHD, similar to HDL cholesterol. Measurement of Apo A-1 and the ratio of Apo B/Apo A-1, provides as good or perhaps better predictive power in assessing risk for CHD than the traditional blood lipids, HDL-cholesterol and the cholesterol/HDL cholesterol ratio.