Test Overview

Test Methodology

Michigan Medicine: Chemiluminescent Immunoassay
Mayo Clinic Laboratories: Enzyme-Linked Immunosorbant Assay (ELISA)

Reference Range*

Females age 12-45 yrs: 0.8 - 9.5 ng/mL, age >45 yrs: <1.0 ng/mL.
AMH performed in the Chemical Pathology Laboratory is measured by the Roche e411 chemiluminescent immunoassay. AMH concentrations in females peak at 25 years and decline with age until menopause. In patients with polycystic ovarian syndrome, AMH concentrations may be 2 to 5 fold higher than age appropriate reference levels. If results are inconsistent with the clinical picture, the Chemical Pathology laboratory at 936-6702.

Testing for all male and female pediatric (age <12 yrs) will be sent to Mayo Clinic Laboratories: Males: age <2 yrs: 14 - 466 ng/mL; age 2-12 yrs: 7.4 - 243 ng/mL; age >12 yrs: 0.7 - 19 ng/mL. Females: age <2 yrs: <4.7 ng/mL; age 2-12 yrs: <8.8 ng/mL.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details

Days Test Performed

Daily

Analytic Time

8 hours

Soft Order Code

AMHS

MiChart Code

Anti-Mullerian Hormone (AMH)

Test Updated

Update Type: New Tests

Updated Date: 09/13/2019

Synonyms

Synonyms

AMH
Mullerian Inhibiting Substance (MIS)
Anti Mullerian Hormone
Antimullerian Hormone, Serum

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Laboratory

Chemical Pathology

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Specimen Requirements

Offsite Collection Instructions

Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. Specimen should be collected on days 2-4 of the menstrual cycle. Samples should not be drawn from patients receiving therapy with high biotin doses (>5 mg/day) until at least 8 hours following the last biotin administration.

Rejection Criteria

EDTA plasma is not acceptable

Container

Yellow Top Tube

Normal Volume

0.5 mL serum

Minimum Volume

0.2 mL serum

Additional Information

Only female patients 12 years and older testing will be performed at Michigan Medicine. All male and female patients <12 years testing will be performed by Mayo Clinic Laboratories.
With the Roche methodology (Chemical Pathology), interference was observed at biotin concentrations above 30 ng/mL. Samples should not be drawn from patients receiving therapy with high biotin doses (>5 mg/day) until at least 8 hours following the last biotin administration.

Billing Information

Fee Codes


CPT Code

Michigan Medicine: 82397, Mayo Clinic Laboratories: 83520

LOINC

Michigan Medicine: 83104-0, Mayo Clinic Laboratories: 38476-8

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