Test Overview
Test Methodology

Laboratory developed Luminex paramagnetic bead multiplex Assay

Test Usage

SmT oncoprotein antibodies are present in the blood of 50% of patients when they have clinically detectable Merkel Cell Carcinoma (MCC). In patients who make oncoprotein antibodies, titers are expected to decrease significantly within 3 months of successful treatment of MCC. Changes in oncoprotein titers of less than 25% may not be biologically significant. A significant rise in titer or stabilization above 2000 STU may be associated with persistent or recurrent MCC.

Reference Range *

Interpretive report provided

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Lipemia may increase results 15-20%

Test Details
Days Set Up
Analytic Time

3 - 4 weeks

Soft Order Code
  • Merkel
Reference Laboratory
University of Washington
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube. Spin and aliquot into a screw capped plastic tube within 4 hours of collection. Send to Specimen Processing refrigerated.

Normal Volume
2mL serum
Minimum Volume
0.5 mL serum
Storage Temperature
Refrigerated stable for 7 days, frozen for long term storage
Additional Information

Test performed by University of Washington Immunology Laboratory