Test Overview
Test Methodology

Spectrophotometric

Test Usage

To support a diagnosis of active sarcoidosis. Prognostic indicator, and for titration of steroid therapy in sarcoidosis. (DeRemee and Rohrbach, Annals of Internal Medicine 92:361-335, 1980).

Reference Range *

16 - 65 IU/L

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Elevations have also been reported in the following: Gaucher's disease, leprosy, berylliosis, Lennert's lymphoma, osteoarthritis, and mycobacterium intracellulare infections. (Lieberman, et al., 'American Review of Respiratory Disease,' 120:329-335, 1979). Treatment of hypertension with converting enzyme inhibitors has been shown to lower serum ACE levels.

Test Details
Days Set Up
Monday, Thursday
Analytic Time

8 hours

Soft Order Code
ACE
MiChart Code
ACE (Angiotensin Converting Enzyme) (LAB179)
Synonyms
  • ACE
  • Angiotensin-1-Converting Enzyme
  • SACE
  • ANGIOTENSIN CONVERTING ENZYME
Laboratory
Chemical Pathology
Section
Special Chemistry
Specimen Requirements
Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into plastic vial and refrigerate; do not freeze. Test should not be ordered following administration of radioisotopes. Avoid hemolysis during collection.

Alternate Specimen
Green top tube.
Yellow Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Additional Information

Freezing of specimen may cause formation of immune complexes, turbidity, or falsely elevated results. Hemolysis (serum free hemoglobin >150 mg/dL) and bilirubin levels >14 mg/dL will interfere with assay results.

Billing
CPT Code
82164
Fee Code
21998
LOINC
2742-5
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