Liquid Chromatography (LC-MS/MS)
Therapeutic drug monitoring
Amiodarone: Therapeutic: 1.5 - 2.5 mcg/mL, Toxic: greater than 3.5 mcg/mL; Desethylamiodarone: Therapeutic: 1.5 - 2.5 mcg/mL, Toxic: greater than 3.5 mcg/mL.
2 - 5 days
- Desethylamiodarone (Amiodarone Metabolite)
Collect blood in a red top tube; do not use SST tube. Centrifuge, aliquot serum or plasma into a plastic vial within 2 hours of collection, and refrigerate (preferred) or freeze. Draw peak levels 2 hours after dose, trough immediately before next dose.
Test sent to Mayo Medical Laboratories.