Test Overview

Test Methodology

Enzymatic End point/Spectrofluorometric

Test Usage

Confirmation of a diagnosis of aminolevulinic acid dehydratase deficiency porphyria (ADP).

Reference Range*

> or = to 4.0 nmol/L/sec (normal), 3.5 - 3.9 nmol/L/sec (indeterminate), <3.5 nmol/L/sec (diminished). Reference ranges have not been established for patients who are <16 years of age.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details

Days Test Performed

Monday, Thursday

Analytic Time

2 - 7 days

Soft Order Code


MiChart Code

Ala Dehydratase, Whole Blood



Aminolevulinic Acid Dehydratase (ALA-D), RBC
ALA Dehydratase, RBC
ALA Dehydratase, BLOOD
ALA Dehydratase, Whole Blood

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Laboratory Reference

Mayo ALAD (88924)

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Specimen Requirements

Offsite Collection Instructions

Patient should abstain from alcohol for 24 hours and be off medications for 1 week prior to specimen collection. If it is clinically inappropriate to discontinue medications, forward a list of medications with the specimen. Collect blood in a green top tube from a fasting patient (12 - 14 hour fast). Place on wet ice immediately. Refrigerate and send intact whole blood within 24 hours of collection.

Special Handing

Fasting specimen. Place on wet ice immediately.

Normal Volume

5 mL heparinized whole blood

Minimum Volume

3 mL heparinized whole blood

Additional Information

Test sent to Mayo Medical Laboratories.

Billing Information

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