Test Overview
Chemiluminescent Immunoassay (CLIA)
To aid in the detection of fetal neural tube defects (NTD).
Interpretive report provided.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
2 - 3 days
- AFP, Maternal Serum
- Maternal Serum AFP
- Neural tube defects (NTD) Risk
Specimen Requirements
Collect specimen in a red top tube from a patient with a maternal gestation of between 16 weeks 0 days and 22 weeks 6 days. Centrifuge, aliquot serum into a plastic vial within 2 hours of collection and refrigerate. Please provide a completed QUAD/AFP Requisition available online at https://mlabs.umich.edu/media/170 or the following information: gestational age (weeks and days on first ultrasound date >6 weeks 0 days; if ultrasound information is not available record first days of last menstrual period), maternal weight, maternal date of birth, insulin-dependent diabetes status prior to pregnancy, multiple gestation (single, twin, triplets), race, and previous history of Down syndrome or neural tube defect (NTD) pregnancy for the patient.
Additional Information
If there is a family history of neural tube defects, consultation with a genetic counselor to more accurately assess increased risk for neural tube defects is recommended. Test sent to Warde Medical Laboratory.