Test Overview

Test Methodology

Chemiluminescent Immunoassay (CLIA)

Test Usage

To aid in the detection of fetal neural tube defects (NTD).

Reference Range*

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details

Days Test Performed

Monday - Friday

Analytic Time

2 - 3 days

Soft Order Code

MAFP

MiChart Code

MATERNAL SCR ALPHA-FETOPROTEIN

Synonyms

Synonyms

AFP, Maternal Serum
Maternal Serum AFP
AFPMS
RAFP
Neural tube defects (NTD) Risk
MSAFP
MULTIPLE OF THE MEDIAN

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Laboratory

Sendout

Laboratory Reference

Warde MSAFP

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Specimen Requirements

Offsite Collection Instructions

Collect specimen in a red top tube from a patient with a maternal gestation of between 16 weeks 0 days and 22 weeks 6 days. Centrifuge, aliquot serum into a plastic vial within 2 hours of collection and refrigerate. Please provide a completed QUAD/AFP Requisition available online at http://mlabs.umich.edu/files/pdfs/REQ-QUAD_refr.pdf or the following information: gestational age (weeks and days on first ultrasound date >6 weeks 0 days; if ultrasound information is not available record first days of last menstrual period), maternal weight, maternal date of birth, insulin-dependent diabetes status prior to pregnancy, multiple gestation (single, twin, triplets), race, and previous history of Down syndrome or neural tube defect (NTD) pregnancy for the patient.

Container

Red Top Tube

Normal Volume

1 mL serum

Minimum Volume

0.6 mL serum

Additional Information

If there is a family history of neural tube defects, consultation with a genetic counselor to more accurately assess increased risk for neural tube defects is recommended. Test sent to Warde Medical Laboratory.

Billing Information

Fee Codes


CPT Code

82105

LOINC

48802-3

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