Chemiluminescent Immunoassay (CLIA)
To aid in the detection of fetal neural tube defects (NTD).
Interpretive report provided.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Days Test Performed
Monday - Friday
2 - 3 days
Soft Order Code
MATERNAL SCR ALPHA-FETOPROTEIN
AFP, Maternal Serum
Maternal Serum AFP
Neural tube defects (NTD) Risk
MULTIPLE OF THE MEDIAN
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Offsite Collection Instructions
Collect specimen in a red top tube from a patient with a maternal gestation of between 16 weeks 0 days and 22 weeks 6 days. Centrifuge, aliquot serum into a plastic vial within 2 hours of collection and refrigerate. Please provide a completed QUAD/AFP Requisition available online at http://mlabs.umich.edu/files/pdfs/REQ-QUAD_refr.pdf or the following information: gestational age (weeks and days on first ultrasound date >6 weeks 0 days; if ultrasound information is not available record first days of last menstrual period), maternal weight, maternal date of birth, insulin-dependent diabetes status prior to pregnancy, multiple gestation (single, twin, triplets), race, and previous history of Down syndrome or neural tube defect (NTD) pregnancy for the patient.
1 mL serum
0.6 mL serum
If there is a family history of neural tube defects, consultation with a genetic counselor to more accurately assess increased risk for neural tube defects is recommended. Test sent to Warde Medical Laboratory.