Test Overview

Test Methodology

Chemiluminescent Immunoassay (CLIA)

Test Usage

To aid in the detection of fetal neural tube defects (NTD).

Reference Range*

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details

Days Test Performed

Monday - Friday

Analytic Time

2 - 3 days

Soft Order Code

MAFP

MiChart Code

MATERNAL SCR ALPHA-FETOPROTEIN

Synonyms

Laboratory

Sendout

Laboratory Reference

Warde MSAFP

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Specimen Requirements

Offsite Collection Instructions

Collect specimen in a red top tube from a patient with a maternal gestation of between 16 weeks 0 days and 22 weeks 6 days. Centrifuge, aliquot serum into a plastic vial within 2 hours of collection and refrigerate. Please provide a completed QUAD/AFP Requisition available online at http://mlabs.umich.edu/files/pdfs/REQ-QUAD_refr.pdf or the following information: gestational age (weeks and days on first ultrasound date >6 weeks 0 days; if ultrasound information is not available record first days of last menstrual period), maternal weight, maternal date of birth, insulin-dependent diabetes status prior to pregnancy, multiple gestation (single, twin, triplets), race, and previous history of Down syndrome or neural tube defect (NTD) pregnancy for the patient.

Container

Normal Volume

1 mL serum

Minimum Volume

0.6 mL serum

Additional Information

If there is a family history of neural tube defects, consultation with a genetic counselor to more accurately assess increased risk for neural tube defects is recommended. Test sent to Warde Medical Laboratory.

Billing Information

Fee Codes

CPT Code

82105

LOINC

48802-3

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