Test Overview
Test Methodology

Chemiluminescent Immunoassay (CLIA)

Test Usage

To aid in the detection of fetal neural tube defects (NTD).

Reference Range *

Interpretive report provided.

Test Details
Days Set Up
Monday - Friday
Analytic Time

2 - 3 days

Soft Order Code
MAFP
MiChart Code
MATERNAL SCR ALPHA-FETOPROTEIN
Synonyms
  • AFP, Maternal Serum
  • Maternal Serum AFP
  • AFPMS
  • RAFP
  • Neural tube defects (NTD) Risk
  • MSAFP
  • MULTIPLE OF THE MEDIAN
Laboratory
Sendout
Reference Laboratory
Warde MSAFP
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube from a patient with a maternal gestation of between 16 weeks 0 days and 22 weeks 6 days. Centrifuge, aliquot serum into a plastic vial within 2 hours of collection and refrigerate. Please provide a completed QUAD/AFP Requisition available online at https://mlabs.umich.edu/media/170 or the following information: gestational age (weeks and days on first ultrasound date >6 weeks 0 days; if ultrasound information is not available record first days of last menstrual period), maternal weight, maternal date of birth, insulin-dependent diabetes status prior to pregnancy, multiple gestation (single, twin, triplets), race, and previous history of Down syndrome or neural tube defect (NTD) pregnancy for the patient.

Alternate Specimen
SST tube is acceptable.
Normal Volume
1 mL serum
Minimum Volume
0.6 mL serum
Storage Temperature
Room Temperature: 7 days; Refrigerated: 7 days; Frozen: 2 months.
Additional Information

If there is a family history of neural tube defects, consultation with a genetic counselor to more accurately assess increased risk for neural tube defects is recommended. Test sent to Warde Medical Laboratory.

Billing
CPT Code
82105
Fee Code
32050
LOINC
48802-3