2 hours
Test Updated:
AFP, CSF
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Test Overview
Chemiluminescent Immunoassay (CLIA)
CSF levels of AFP are a useful aid in the diagnosis of primary central nervous system (CNS) germ cell tumors (GCTs). These account for approximately 4 % of primary brain tumors in children. AFP elevation in CSF occurs in approximately 70 % of these tumors. Concurrent testing of beta-HCG is recommended to improve the sensitivity for detecting these CNS tumors. CSF levels of AFP will also be elevated with brain metastases of testicular cancer.
0 - 1 ng/mL
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimen Requirements
Collect spinal fluid, refrigerate.