Hydrolysis of Synthetic Chromogenic Substrate, Colorimetric End point.
Providing a more complete assessment of disseminated intravascular coagulation, intravascular coagulation and fibrinolysis, or hyperfibrinolysis (primary fibrinolysis), when measured in conjunction with fibrinogen, fibrin D-dimer, fibrin degradation products, soluble fibrin monomer complex, and plasminogen; Evaluating liver disease or the effects of fibrinolytic or antifibrinolytic therapy; Diagnosing congenital alpha-2 plasmin inhibitor deficiencies (rare).
80 - 140% (adults). Normal, full-term newborn infants may have borderline low or mildly decreased levels (> or =50%) which reach adult levels within 5-7 days postnatal. Healthy, premature infants (30-36 weeks gestation) may have
mildly decreased levels which reach adult levels in < or =90 days postnatal.
- Alpha 2 Antiplasmin
- Alpha-2 Proteinase Inhibitor
Collect specimen in blue top (citrate) tube. Centrifuge specimen and aliquot citrate platelet-poor plasma into a plastic tube. Centrifuge plasma again and aliquot platelet-poor plasma into a plastic vials (no glass). Freeze plasma immediately at <40 degrees C. Transport frozen specimen on dry ice. Proper collection and handling of specimens is critical; see Coagulation tab of the handbook to ensure that the proper technique is used.
Test is sent to Mayo Medical Laboratories.