Days Set Up
Monday-Friday, varies
Analytic Time

2-8 days

Soft Order Code

Test Updated:


Alpha 2 Antiplasmin
Alpha-2 Proteinase Inhibitor

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Find a Requisition

All specimens should be accompanied by a requisition.

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Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

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Test Overview

Test Methodology

Hydrolysis of Synthetic Chromogenic Substrate, Colorimetric End point.

Test Usage

Providing a more complete assessment of disseminated intravascular coagulation, intravascular coagulation and fibrinolysis, or hyperfibrinolysis (primary fibrinolysis), when measured in conjunction with fibrinogen, fibrin D-dimer, fibrin degradation products, soluble fibrin monomer complex, and plasminogen; Evaluating liver disease or the effects of fibrinolytic or antifibrinolytic therapy; Diagnosing congenital alpha-2 plasmin inhibitor deficiencies (rare).

Reference Range

80 - 140% (adults). Normal, full-term newborn infants may have borderline low or mildly decreased levels (> or =50%) which reach adult levels within 5-7 days postnatal. Healthy, premature infants (30-36 weeks gestation) may have
mildly decreased levels which reach adult levels in < or =90 days postnatal.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect specimen in blue top (citrate) tube. Centrifuge specimen and aliquot citrate platelet-poor plasma into a plastic tube. Centrifuge plasma again and aliquot platelet-poor plasma into a plastic vials (no glass). Freeze plasma immediately at <40 degrees C. Transport frozen specimen on dry ice. Proper collection and handling of specimens is critical; see Coagulation tab of the handbook to ensure that the proper technique is used.

Blue Top Tube
Normal Volume
1 mL plasma
Minimum Volume
0.5 mL plasma

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.