Test Overview
Test Methodology

Chemiluminescence

Test Usage

Adrenal function test, evaluation of renal hypertension.

Reference Range *

Upright: 4-31 ng/dl; Supine: 1-16 ng/dl

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Tuesday, Friday
Analytic Time

8 hours

Soft Order Code
SALDO
MiChart Code
Aldosterone
Synonyms
    Laboratory
    Chemical Pathology
    Section
    Special Chemistry
    Specimen Requirements
    Collection Instructions

    Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and freeze.

    Alternate Specimen
    EDTA Plasma tube acceptable
    Normal Volume
    1 mL serum
    Minimum Volume
    0.5 mL serum
    Additional Information

    Aldosterone values are best interpreted with simultaneous plasma renin measurement when screening for primary aldosteronism.

    1) If simultaneous plasma renin mass is less than 8 pg/mL and:
    · aldosterone of less than 10 ng/dL: Unlikely primary aldosteronism
    · aldosterone of 10 to 20 ng/dL: Possible primary aldosteronism
    · aldosterone of greater than 20 ng/dL: Suggestive of primary aldosteronism
    2) If simultaneous plasma renin mass is greater than or equal to 8 pg/mL and:
    · the ratio of serum aldosterone to direct plasma renin mass is greater than 2.6 (ng/dL:pg/mL), findings are suggestive of primary aldosteronism

    Multiple factors including medications, sodium status, and other causes may influence these values and could potentially lead to false-positive or false-negative results; these factors should be considered in interpretation as noted in Endocrine Society guidelines [Funder JW et al. J Clin Endocrinol Metab. 2016, 101(5):1889-1916].

    Billing
    CPT Code
    82088
    Fee Code
    32035
    LOINC
    1763-2
    NY State Approved
    No