Days Set Up
Analytic Time

8 hours

MiChart Code
5 HIAA, 24 HR Urine
Soft Order Code

Test Updated:


5-Hydroxytryptamine Metabolite
Hydroxyindoleacetic Acid, 5-
Hydroxytryptamine, 5- Metabolite
Serotonin Metabolite

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All specimens should be accompanied by a requisition.

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Test Overview

Test Methodology

High Performance Liquid Chromatography (HPLC)

Test Usage

Aid in the diagnosis of carcinoid tumors.

Reference Range

3 - 10 mg/24 hrs (15.6-52.0 uMol/24 hrs).

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect 24 hour urine specimen. Add 25 mL of 50% glacial acetic acid (15 mL for pediatric patients) to container prior to start of collection. Following collection, mix well, measure 24 hour urine volume, aliquot 10 mL into a plastic urine container and refrigerate. Record total 24 hour urine volume and collection dates/times on request form. Specimens with no preservative are also acceptable: add 50% glacial acetic acid to container following collection, mix well and send 10 mL aliquot (preferred); alternatively a non-acidified aliquot will be accepted. Patient should avoid bananas, pineapple, walnuts, chocolate, kiwi, cough medicine and avocados prior to and during collection; also phenothiazines should be withheld for several days prior to collection if possible.

Red Top Tube
Normal Volume
10 mL aliquot of 24 hour urine collection
Minimum Volume
10 mL aliquot of 24 hour urine collection

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.