Update Type: Replacement Test
Test Updated: 06/09/2021
Test Overview
Test Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Screening for mast cell activation disorders including systemic mastocytosis

Reference Range *

<1802 pg/mg creatinine

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Elevated levels of 2,3-dinor-11beta-prostaglandin F2 alpha (2,3 BPG) in urine are not specific for systemic mast cell disease and may be found in patients with angioedema, diffuse urticaria, or myeloproliferative diseases in the absence of diffuse mast cell proliferation

Test Details
Days Set Up
Tuesday, Thursday
Analytic Time

3 - 8 days

Soft Order Code
23BPR / 23BPT
Reference Laboratory
Mayo 23BPR / Mayo 23BPT
Special Testing
Specimen Requirements
Collection Instructions

Collect urine in a plastic container. Send to Specimen Processing refrigerated.

Alternate Specimen
Refrigeration is the preferred preservative. But acceptable others are: 50 % acetic acid, boric acid or sodium carbonate.
Normal Volume
5 mL urine
Minimum Volume
4 mL urine
Storage Temperature
Refrigerated preferred, frozen is acceptable
Additional Information

Test performed by Mayo Clinic Laboratories

CPT Code
Fee Code