Test Overview
Test Methodology

Immunoabsorption Assay

Test Usage

Investigation of adrenal insufficiency and aid in the detection of those at risk of developing autoimmune adrenal failure. Positive results indicate the presence of adrenal autoantibodies consistent with Addison's disease. Research Use Only.

Reference Range *

< 1 U/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Wednesday
Analytic Time

3 - 10 days

Soft Order Code
OH21
MiChart Code
Adrenal Antibodies, 21-Hydroxylase
Synonyms
  • Adrenal Antibody
  • Anti-adrenal Antibodies
  • 21-OH Antibody
  • ACAB
  • Adrenal Cortex Antibodies
  • Hydroxylase Antibodies, 21-
  • OH21
  • Adrenal Antibodies, 21-Hydroxylase
Laboratory
Sendout
Reference Laboratory
Mayo OH21 (81970)
Section
Special Testing
Specimen Requirements
Collection Instructions

Collect blood in a red top tube. Centrifuge, aliquot serum into a plastic vial and freeze.

Red Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.2 mL serum
Additional Information

The microsomal autoantigen 21-hydroxylase (55 kilodalton) has been shown to be the primary autoantigen associated with autoimmune Addison's disease. 21-Hydroxylase antibodies are markers of autoimmune Addison's disease, whether it presents alone, or as part of Type I or Type II (APS). Test sent to Mayo Medical Laboratories.

Billing
CPT Code
83519
Fee Code
22001
LOINC
17781-6
Resources