Posted Date
Effective Date
Update Type Miscellaneous
CPT Code 86255 x12, 84182
Order Code AIAES

TEST PANEL UPDATE

 

Axonal Neuropathy, Autoimmune Evaluation, Serum

Order Code:                  AIAES

Fee Code:                     AA980, AA981 (CPT 86255 x12, 84182)

New CPT Codes:          86255 x10                    

Reference Laboratory:   Mayo AIAES

 

The following changes will be made to the Axonal Neuropathy, Autoimmune Evaluation, Serum, assay performed by Mayo Clinic Laboratories effective October 13, 2026:

 

The following test will be added to the panel:

  • Collapsin Response-Mediator Protein-5 Neuronal (CRMP-5-IgG), Serum (CRMS)

 

The following tests will be removed from the panel:

  • Collapsin Response-Mediator Protein-5-IgG, Western Blot, Serum (CRMWS)
  • Glial Fibrillary Acidic Protein Alpha Subunit Antibody, Immunofluorescence, Serum (GFAIS)
  • Neuronal Intermediate Filament IgG, Immunofluorescence, Serum (NIFIS)
  • Purkinje Cell Cytoplasmic Antibody, Type 1 (PCA-1), Serum (PCABP)

 

The following tests will be added to the reflex algorithm:

  • Collapsin Response-Mediator Protein-5-IgG, Western Blot, Serum (CRMWS)
  • Microtubule-Associated Protein 1B (MAP1B) Antibody, Immunoblot, Serum (MP1BS)

 

The following tests will be removed from the reflex algorithm:

  • Alpha Internexin, Cell Binding Assay, Serum (AINCS) 
  • Glial Fibrillary Acidic Protein Alpha Subunit Antibody, Cell Binding Assay, Serum (GFACS) 
  • Glial Fibrillary Acidic Protein Alpha Subunit Antibody, Immunofluorescence Titer Assay, Serum  (GFATS) 
  • Neuronal Intermediate Filament Heavy Chain, Cell Binding Assay, Serum (NFHCS) 
  • Neuronal Intermediate Filament Light Chain, Cell Binding Assay, Serum (NFLCS)
  • Neuronal Intermediate Filament IgG, Immunofluorescence Titer Assay, Serum (NIFTS)
  • Purkinje Cell Cytoplasmic Antibody-Type 1, Immunoblot, Serum (PC1BS)
  • Purkinje Cell Cytoplasmic Antibody Type 1 (PCA-1) Titer, Serum (PC1TS)