Posted Date
Effective Date
Update Type Miscellaneous
CPT Code 86255 x13, 86341, 86053   
Order Code PCDEC

Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, CSF

Order Code:                  PCDEC

Fee Code:                     AA977, AA978, AA997 (CPT 86255 x11, 86341, 86053)

New CPT Codes:          86255 x13, 86341, 86053                      

Reference Laboratory:   Mayo PCDEC

 

The following changes will be made to the Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, CSF, assay performed by Mayo Clinic Laboratories effective October 13, 2026:

 

The following tests will be added to the panel:

  • Metabotropic Glutamate Receptor-5 (mGluR5) IgG, Tissue Immunofluorescence, Spinal Fluid (GL5IC)
  • Gamma-Amino Butyric Acid Type A (GABA-A) Receptor Antibody, Cell-Binding Assay, Spinal Fluid (GBACC)

 

The following tests will be added to the reflex algorithm:

  • Metabotropic Glutamate Receptor-5 (mGluR5) IgG, Cell Based Assay, Spinal Fluid (GL5CC)
  • Metabotropic Glutamate Receptor-5 (mGluR5) IgG, Tissue Immunofluorescence Titer, Spinal Fluid (GL5TC)