Test Name Syphilis Screening Test, VDRL, CSF
Posted Date
Effective Date
Update Type Test Discontinued
CPT Code 86592
Order Code VDSF

Syphilis Screening Test, VDRL, CSF

Order Code:                  VDSF

Fee Code:                     21925 (CPT 86592)

Reference Laboratory:   Mayo VDSF

 

Mayo Clinic Laboratories will discontinue their VDRL, Spinal Fluid, assay and replace it with Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid effective May 22, 2025. The new method is preferred over the classic VDRL assay for the following reasons:

  1. The new method assesses for T. pallidum-specific antibodies, rather than the non-treponemal antibodies that are detected by the VDRL method
  2. The new method assesses for intrathecally synthesized T. pallidum antibodies in the CSF (i.e., the method corrects for any passive diffusion of antibodies from serum into the CSF
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