NEW TEST FOR INPATIENT ORDERS
CSF Analysis with reflex to MEPAN
Order Code: MRP
Fee Code: 22502, 22226, 22228 (CPT 89051, 82945, 84157
Michigan Medicine Laboratories will begin offering a new test for inpatient orders, CSF Analysis with reflex to MEPAN (order code MRP), effective April 16, 2025.
MRP will include the following components:
| CSFCD | Cerebrospinal Fluid Count and Differential |
| GLCSF | Glucose Level, CSF |
| PRCSF | Protein Level, CSF |
| MPRT | MEPAN Reflex Request |
When MRP is ordered, the Meningitis/Encephalitis Panel (order code MEPAN) will be automatically performed on CSF specimens that meet any of the following criteria:
- WBC > 5 cells/mm³
- Protein > 50 mg/dL
- Glucose < 40 mg/dL
The MEPAN assay can also be ordered independently (requires Michigan Medicine Infectious Disease or Laboratory Director approval for MLabs client orders) when used as recommended by febrile infant guidelines (0-60 days old).
The BioFire® Meningitis/Encephalitis PCR Panel (MEPAN) detects 14 common viral, bacterial, and fungal pathogens that cause meningitis and encephalitis, provides rapid results (within 1–2 hours of receipt) and is available 24 hours a day, 7 days a week.
Note that standalone testing for Enterovirus has been discontinued by the manufacturer but is available as a routine part of this panel.