Posted Date
Effective Date
CPT Code 86255 x21, 86341
Order Code ENC2
Referral Laboratory Mayo Medical Laboratories

Encephalopathy, Autoimmune Evaluation, CSF

Order Code:                  ENC2

Fee Code:                    AA271, AA270 (CPT 86255 x21, 86341)

Reference Laboratory:   Mayo ENC2

 

Effective June 4, 2024, the following updates will be made to Mayo Clinic Laboratories Encephalopathy Autoimmune Evaluation, CSF, panel:

 

Additions:

  • Test component Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence, CSF (test ID T46IC) (CPT 86255) will be added to the panel.
  • Test component Phosphodiesterase 10A (PDE10A) IgG, Tissue Immunofluorescence, CSF (test ID PDEIC) (CPT 86255) will be added to the panel.
  • Test component Dipeptidyl-Peptidase-Like Protein-6 (DPPX) Antibody, Cell Binding Assay, CSF (test ID DPPCC) (CPT 86255) will be added to the panel.
  • Test component IgLON Family Member 5 Antibody, Cell Binding Assay, CSF (test ID IG5CC) (CPT 86255) will be added to the panel.
  • Reflex test Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Cell Binding Assay, CSF (test ID T46CC) (CPT 86255) will be performed automatically at an additional charge if indicated.
  • Reflex test Tripartite Motif-Containing Protein 46 (TRIM46) IgG, Tissue Immunofluorescence Titer, CSF (test ID T46TC) (CPT 86256) will be performed automatically at an additional charge if indicated.
  • Reflex test Phosphodiesterase 10A (PDE10A) IgG, Tissue Immunofluorescence Titer, CSF (test ID PDETC) (CPT 86256) will be performed automatically at an additional charge if indicated.

 

Deletions:

  • Test component Dipeptidyl-Peptidase-Like Protein-6 (DPPX) Antibody, Immunofluorescence, CSF (test ID DPPIC) (CPT 86255) will be removed from the panel.
  • Test component IgLON Family Member 5 Antibody, Immunofluorescence, CSF (test ID IG5IC) (CPT 86255) will be removed from the panel.

 

Note that DPPCC and IG5CC will become always performed panel components instead of potential reflex tests.