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NEWS & EVENTS

U-M Pathology Hosts Inaugural Global Pathology Summit

The Department of Pathology recently hosted its first Global Pathology Summit, marking a significant step in addressing health disparities through advancements in pathology. Dr. Rouba Ali-Fehmi, the summit director, welcomed attendees and highlighted the essential role of global pathology in healthcare, the transformative potential of digital pathology and artificial intelligence (AI), and the importance of sustainable partnerships.

New MLabsConnect Feature to Reset Passwords

Effective today, MLabs has launched a new feature to allow users to reset forgotten passwords on MLabsConnect. This new feature requires MLabsConnect Users to create a security question and personalized answer.

Pathology Honors Years of Service and Above and Beyond Awardees

Faculty and staff from across the Department of Pathology gathered over the lunch hour on Friday, October 4th, to honor their colleagues at the annual Workplace Recognition Reception.

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Featured Test

 

FGFR Mutation/Translocation


Erdafitinib (Balversa™) is an FGFR-inhibitor that is FDA-approved for the treatment of metastatic urothelial cancers harboring susceptible mutations or translocations involving FGFR2 or FGFR3. 
 

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NCRC Staff

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Myeloid NGS Panel

This test is intended for the molecular evaluation of myeloid neoplasms including myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), myelodysplastic/myeloproliferative neoplasms, acute myeloid leukemias (AML), mastocytosis and myeloid neoplasms with eosinophilia and gene rearrangement.


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TFE3 Rearrangement (FISH)

 Detecting rearrangements involving the TFE3 gene region (Xp11.2) via fluorescence in situ hybridization (FISH) to qualitatively assess for the presence of TFE3 translocations that are associated with certain subtypes of renal cell carcinoma. Testing for TFE3 gene rearrangement may aid in the diagnosis and classification of renal tumors.


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NCRC Staff

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NGS Solid Tumor Panel


Molecular testing of solid tumor neoplasms - particularly advanced-stage cancer. This DNA and RNA based, NGS test targets 50 actionable genes (35 mutations, 19 amplifications, 21 - fusions). Requires <1mm2 of tissue (as little as 100 tumor cells) and a low 3% QNS rate. 

 

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PIK3CA Mutation: 

NEW TREATMENT OPTION FOR METASTATIC BREAST CANCER

MLabs offers NGS Solid Tumor Panel and Single gene test to detect PIK3CA for FDA approved therapy alpelisib (Piqray®).


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Featured Test

 

NR4A3 (9q22-9q31) Rearrangement (FISH)

NR4A3 encodes an orphan nuclear receptor. Rearrangements of NR4A3 occur in more than 80% of extraskeletal myxoid chondrosarcoma (EMC) as well as in salivary acinic cell carcinoma (AciCC), driving tumorigenesis. 


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