Days Set Up
Monday - Friday
Analytic Time

8 hours

MiChart Code
Varicella Zoster Antibody, IgG
Soft Order Code
VZVG

Test Updated:

Synonyms

Varicella IgG, Qualitative
VZVG
Chicken Pox Antibody, IgG
Shingles Antibody, IgG
Viral Antibody: Varicella zoster IgG
VZV, IgG
VZVGE
VZV IGG ANTIBODY BY EIA
VZV IgG Antibody, Index
VZV IgG Antibody, Qualitative
VZVGN
VZVGI
VZV IgG, Index

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Test Overview

Test Methodology

Chemiluminescent Immunoassay

Test Usage

Support the diagnosis of Varicella Zoster virus infection. The presence of IgG antibody generally indicates past exposure and immunity. The presence of IgM antibody or a fourfold or greater rise in IgG antibodies in paired sera indicates recent infection. Single IgG levels are not useful for supporting the diagnosis of acute infection. Elevated levels in neonates should be followed up with studies to rule out the presence of maternal antibodies, either by obtaining a convalescent specimen or by the demonstration of the absence of an IgM response.

Reference Range

NEGATIVE: <135 Index. Absence of detectable VZV IgG antibodies. A negative result does not rule out acute infection. The test can be negative in infected patients during the incubation period and the early stages of infection. If exposure to varicella zoster virus is suspected, a second sample should be collected and tested 1-2 weeks later. EQUIVOCAL: 135 - 165 Index. A second sample should be collected and tested. POSITIVE: >165 Index. Presence of detectable VZV IgG antibodies. A positive result indicates exposure to the pathogen or administration of specific immunoglobulins. It is not an indication of active infection or stage of disease.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in an SST (preferred) or red top tube.

Collection Offsite

Collect specimen in an SST (preferred) or red top tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. Post-vaccination samples should be collected 4-6 weeks from the date of vaccination.

Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.3 mL serum

Billing Information

CPT Code
86787
Pro Fee Code
 
LOINC
15410-4

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.