Test Overview
Test Methodology

Multiplex Flow Immunoassay

Test Usage

SS-A (Ro) and SS-B (La) antibodies have a strong association with Sjogen’s syndrome and can be used to support the clinical diagnosis. SS-A is present in 70 - 75% and SS-B in 60 - 65% of patients with Sjogren’s syndrome. However, both SS-A and SS-B antibodies are present in SLE and other connective tissue disorders, so their presence must be interpreted in the clinical context. The BioPlex 2200 test system uses an affinity purified SS-A 60 antigen, a second SS-A 52 recombinant antigen, and an affinity purified SS-B antigen.

Reference Range *

Negative

Test Details
Days Set Up
Monday - Friday
Analytic Time

24 hours

Soft Order Code
SSB
MiChart Code
Sjogrens syndrome-B extractable nuclear antibody
Laboratory
Chemical Pathology
Section
Immunopathology
Specimen Requirements
Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Alternate Specimen
Red top tube.
Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum
Billing
CPT Code
86235
Fee Code
30930
NY State Approved
No