Days Set Up
Monday - Friday
Analytic Time

24 hours

MiChart Code
Sjogrens syndrome-B extractable nuclear antibody
Soft Order Code

Test Updated:


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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

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MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Multiplex Flow Immunoassay

Test Usage

SS-A (Ro) and SS-B (La) antibodies have a strong association with Sjogen’s syndrome and can be used to support the clinical diagnosis. SS-A is present in 70 - 75% and SS-B in 60 - 65% of patients with Sjogren’s syndrome. However, both SS-A and SS-B antibodies are present in SLE and other connective tissue disorders, so their presence must be interpreted in the clinical context. The BioPlex 2200 test system uses an affinity purified SS-A 60 antigen, a second SS-A 52 recombinant antigen, and an affinity purified SS-B antigen.

Reference Range


* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.