Test Overview
Test Methodology

Multiplex Flow Immunoassay

Test Usage

SS-A (Ro) and SS-B (La) antibodies have a strong association with Sjogen’s syndrome and can be used to support the clinical diagnosis. SS-A is present in 70 - 75% and SS-B in 60 - 65% of patients with Sjogren’s syndrome. However, both SS-A and SS-B antibodies are present in SLE and other connective tissue disorders, so their presence must be interpreted in the clinical context. The BioPlex 2200 test system uses an affinity purified SS-A 60 antigen, a second SS-A 52 recombinant antigen, and an affinity purified SS-B antigen.

Reference Range *


* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Days Set Up
Monday - Friday
Analytic Time

24 hours

Soft Order Code
MiChart Code
Sjogrens syndrome-B extractable nuclear antibody
Chemical Pathology
Specimen Requirements
Collection Instructions

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Alternate Specimen
Red top tube.
Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum
CPT Code
Fee Code