Days Set Up
Analytic Time

4 - 14 days

MiChart Code
Soluble Liver Antigen (SLA) IgG Ab (Sendout)
Soft Order Code

Test Updated:


SLA IgG Antibody

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Test Overview

Test Methodology

Enzyme Linked Immunosorbent Immunoassay

Test Usage

Antibodies to soluble liver antigen (SLA) appear to be directed against the UGA-suppressor tRNA associated protein. These antibodies are highly specific for autoimmune hepatitis (AIH) and may, rarely, be the only autoantibodies detected in serum from such patients. Antibodies to SLA are most closely associated with AIH type1; the presence of these antibodies in patients with cryptogenic hepatitis suggests that these patients may have AIH type 1. Anti-SLA antibodies may be detected in some patients with the primary biliary cirrhosis-AIH overlap syndrome, but not in healthy controls.

Reference Range

Negative: 0.0 - 20.0 U; Equivocal: 20.1 - 24.9 U; Positive: >or=25.0 U

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in a red top or SST tube.

Collection Offsite

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Red Top Tube
Yellow Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.3 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.