Test Overview
Test Methodology

Molecular Typing (SSO)

Test Usage

At the UMHS Histocompatibility Laboratory potential recipients are typed for HLA-A, B, C, DRB1,3,4,5, DQB1, DQA1 loci by medium/low resolution molecular methods (Antigen level). When a potential related or unrelated living donor is considered for transplant, the HLA typing of the donor is performed to evaluate compatibility. Donors are typed for the same HLA loci and for DPB1 in case of anti-HLA DPB1 detected on the recipient serum. The lymphocyte crossmatch assesses the level of circulating antibodies in the potential recipient that are directed against HLA Class I and/or Class II molecules of the donor.

Reference Range *

Interpretive report provided.

Test Details
Days Set Up
Monday - Thursday, 8:00am - 4:30pm; Friday 8:00am - 10:30am
Analytic Time

5 days

Soft Order Code
HLSOD
Synonyms
  • HLA REPORT
  • HLA Class I Low Resolution
  • HLA Class II Low Resolution
  • HLSOD
  • HLFXM
  • TISSUE TYPING
  • TTYPE
  • SOND
  • New Kidney Donor
  • Kidney Transplant Donor
  • Flow Crossmatch, Kidney Donor
  • HLA Crossmatch Flow
  • HLA Typing Class I and II
Laboratory
Histocompatibility/Immunogenetics
Section
Histocompatibility
Specimen Requirements
Collection

Collect specimen in sufficient yellow top (ACD) solution A tubes. Send intact specimen at room temperature. Do not refrigerate or freeze.

Alternate Specimen
Yellow top ACD (Solution B) tube , lavender top EDTA tube, Green top (sodium or lithium heparin) tube
Normal Volume
10 mL ACD (solution A) whole blood
Minimum Volume
10 mL ACD (solution A) whole blood
Additional Information

Test includes HLA Typing Class I & II.

Billing
CPT Code
81370, 81376 x3
Fee Code
OA006, OA007 x3
Reflex Fee Code
10383
NY State Approved
No