Days Set Up
Monday - Thursday, 8:00am - 4:30pm; Friday 8:00am - 2:00pm
Analytic Time

STAT: 48 hours; Routine: 5 days

Soft Order Code

Test Updated:


HLA Antibody Specificity Class II
HLA Antibody Specificity Class I
Donor Specific Ab Testing
Donor Specific Antibody (DSA)
Class I & II SAB Antibody Screening

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Solid Phase Antibody Screening

Test Usage

The antibodies directed to the possible donor or an already transplanted organ are known as Donor Specific Antibodies (DSA). These DSA are associated with an increased risk of graft loss and/or rejection. The damage produced by the recognition of the HLA antigens on the surface of the graft endothelium by the DSA result in the rejection process known as Antibody Mediated Rejection (AMR).
The high specificity and sensitivity of the current solid phase single antigen assay allow us the detection of low-level of the precise DSA. The detection of DSA in pre-transplant evaluation is an excellent tool for risk assessment and crossmatch prediction (Virtual Crossmatch and CPRA). The routine monitoring of DSA in the post-transplant setting assist the transplant team in the characterization of the rejection process and the treatment decisions.

Reference Range

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements


Collect specimen in a red top (preferred) or SST tube. Send intact specimen at room temperature. Do not refrigerate or freeze. Specify whether testing is STAT or routine.

Yellow Top Tube
Red Top Tube
Normal Volume
5 mL serum
Minimum Volume
2 mL serum

Billing Information

CPT Code
86832, 86833
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.