Days Set Up
Tuesday, Friday
Analytic Time

8 hours

MiChart Code
Soft Order Code

Test Updated:


Antismooth Muscle Antibody
Liver Smooth Muscle Antibody
Smooth Muscle Antibody

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All specimens should be accompanied by a requisition.

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Test FAQ

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Test Overview

Test Methodology

Indirect Fluorescent Antibody (IFA), Mouse stomach kidney substrate

Test Usage

Positive in 50-80% of patients with chronic active hepatitis. Titers are negative in extra hepatic biliary obstruction. Antismooth muscle antibodies (SMA) are also seen in acute viral hepatitis; low titers may be seen in primary biliary cirrhosis.

Reference Range


* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in SST tube.Specimen aliquot should be frozen if it's not going to be received in Immunology within 3 days of collection.

Collection Offsite

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. Specimen aliquot should be frozen if it's not going to be received in Immunology within 3 days of collection.

Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.2 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.