Label a CytoLyt container with patient last name, first name and registration number (or other second unique patient identifier). Brush lesion area. Place brush directly into CytoLyt, swirl the brush vigorously in the solution, then snip into the container. Submit with an appropriately completed requisition, including pertinent patient history. Deliver immediately to Specimen Processing or to the Cytopathology Laboratory during laboratory hours. Refrigerate specimens that cannot be delivered during laboratory hours and deliver as soon as possible the following work day. Do not allow specimen to freeze. If CytoLyt is not available, label a slide with patient's last name, first name and registration number (or other second unique patient identifier) using a graphite pencil (do not use ink, wax or crayon). Gently roll brush on glass slide to cover the area of a dime and fix each smear immediately with spray fixative. Allow spray-fixed slides to dry completely and place into a slide holder. Submit with an appropriately completed requisition, including pertinent patient history. Deliver slide holder with completed requisition to Specimen Processing or to the Cytopathology Laboratory during laboratory hours.