Analytic Time

10 days

MiChart Code
Anti-SAE
Soft Order Code
LSAE

Test Updated:

Synonyms

Anti-SAE 1 IgG

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Test Overview

Test Methodology

EIA

Test Usage

Anti-SAE 1 IgG autoantibody can be used to assist in the diagnoses and characterization of a subset of dermatomyositis (DM) patients. It is highly specific for DM (>95%) and is present in 5-8% of the European DM population. Initial disease onset may consist of mild myopathic features with severe skin involvement; however, extensive myalgia and muscle disease with weakness can appear as the disease progresses. It is associated with dysphagia and systemic symptoms (i.e. fevers, weight loss, increased inflammatory markers). In one cohort, an association with ILD and cancer had been found.

Reference Range
 

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection

Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. Plasma is also acceptable (EDTA, heparin, or citrate).

Yellow Top Tube
Normal Volume
1 mL serum
Minimum Volume
 

Billing Information

CPT Code
83520
Pro Fee Code
 
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.