Days Set Up
Monday - Friday
Analytic Time

6-11 days

Soft Order Code
FPD2U

Test Updated:

Synonyms

PG D2
PGD2

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All specimens should be accompanied by a requisition.

Submitting Specimens

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Test Overview

Test Methodology

EIA following extraction of specimens.

Test Usage

Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin.

Reference Range

35 - 115 pg/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in a red top or lavender top tube. Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.

Collection Offsite

Collect specimen in a red top (preferred) or SST tube. Centrifuge, aliquot serum or plasma into a plastic vial and freeze. Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.

Red Top Tube
Yellow Top Tube
Normal Volume
3 mL serum
Minimum Volume
1 mL serum

Billing Information

CPT Code
84150
Pro Fee Code
 
LOINC
12839-7

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.