Days Set Up
Tuesday, Thursday
Analytic Time

2 - 6 days

MiChart Code
Procollagen Type 1 Intact N-terminal Propeptide (P1NP), (MAYO-FPNTS)
Soft Order Code

Test Updated:



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Test Overview

Test Methodology

Radioimmunoassay (RIA)

Test Usage

An aid in monitoring antiresorptive and anabolic therapy in patients with osteoporosis. An adjunct in the assessment of conditions associated with increased bone turnover such as Paget disease. Procollagen I Intact N-terminal (PINP) values should not be used as a screening test for osteoporosis in the general population.

Reference Range

Reference values have not been established for patients who are less than 18 years of age. Adult male: 22 - 87 mcg/L; Adult female premenopausal: 19 - 83 mcg/L; Adult female post menopausal: 16 - 96 mcg/L.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements


This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. Collect blood in red top tube (SST is acceptable). Centrifuge, aliquot serum into a plastic vial, and freeze (preferred) or refrigerate.

Red Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.