Days Set Up
Monday - Friday
Analytic Time

2 - 3 days

MiChart Code
Porphyrins, Quant, 24 Hour Urine
Soft Order Code

Test Updated:


Porphyrins, Fractionation, Urine

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Test Overview

Test Methodology

High-Performance Liquid Chromatography (HPLC) with Fluorometric Detection

Test Usage

Screening test during symptomatic periods for acute intermittent porphyria, hereditary coproporphyria, and variegate porphyria (additional confirmatory testing is required to establish a diagnosis). Screening test to begin assessment for congenital erythropoietic porphyria and porphyria cutanea tarda (additional confirmatory testing is required to establish a diagnosis).

Reference Range

UROPORPHYRINS (octacarboxyl): < or =30 nmol/24 hours. HEPTACARBOXYLPORPHYRINS: < or =9 nmol/24 hours. HEXACARBOXYLPORPHYRINS: < or =8 nmol/24 hours. PENTACARBOXYLPORPHYRINS: < or =10 nmol/24 hours. COPROPORPHYRINS (tetracarboxyl): Males: < or =230 nmol/24 hours; Females: < or =168 nmol/24 hours. PORPHOBILINOGEN: < or =2.2 mcmol/24 hours.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements


Patient should abstain from alcohol for 24 hours prior to, as well as during, collection. Collect 24 hour urine specimen. Add 5 grams of Sodium Carbonate (1 gram for pediatric patients) to container prior to start of collection; do not use Sodium Bicarbonate. The container should be refrigerated and protected from light as much as possible during collection. Following collection, mix well, measure 24 hour urine volume, aliquot 50 mL into a plastic urine container and freeze. Protect specimen from light. Record total 24 hour urine volume and collection dates/times on request form.

Normal Volume
50 mL aliquot of 24 hour urine collection
Minimum Volume
20 mL aliquot of 24 hour urine collection

Billing Information

CPT Code
84120, 84110
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.