Platelet Refractory Consult
Platelet Refractoriness Evaluation
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Evaluation by the blood bank house officers to determine if further testing should be performed to determine immune-based platelet refractoriness.
Platelet refractoriness evaluation should be ordered on patients who show consistent failure to respond to transfused platelets and in whom significant non-immune causes of platelet refractoriness have been excluded. If the initial evaluation is suggestive of immune refractoriness, the care team will be contacted to draw 2 pink-top tubes for further evaluation of platelet refractoriness by platelet cross-match with random donors performed at the Red Cross in Detroit. If the cross-match evaluation shows a high degree of immune refractoriness, the patient’s previously drawn blood will be evaluated for anti-HLA antibodies. If this evaluation shows a high degree of anti-HLA antibodies, then HLA-matched platelets will be ordered for the patient.
Not platelet refractory, non-immune platelet refractory, or suspicious for immune platelet refractory.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
1-hour post-transfusion platelet levels should be drawn after transfusion of any cross-matched or HLA-matched platelets to evaluate the benefit to the patient.
This test is available only for University of Michigan registered patients.