8 hours
Test Updated:
Anti-parietal Cell Antibody
PAC
PARIETAL CELL ANTIBODY
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Test Overview
Indirect Fluorescent Antibody (IFA), Mouse stomach kidney substrate.
Useful in the diagnosis of pernicious anemia in which approximately 80% of patients demonstrate antibodies. A positive test in the presence of a megaloblastic anemia makes pernicious anemia a probable diagnosis. A negative test will help differentiate pernicious anemia from other anemias and Whipple's disease. Rarely, antiparietal cell antibodies are found in patients with gastric ulcer, atrophic gastritis, chronic thyroiditis, iron deficiency anemia, juvenile diabetes mellitus, idiopathic Addison's disease, gastric carcinoma, and in the normal population.
Negative
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimen Requirements
Collect specimen in SST tube. Specimen should be frozen if it's not going to be received in Immunology within 3 days of collection.
Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate for up to 3 days. Specimen should be frozen if it's not going to be received in Immunology within 3 days of collection.
