2 - 5 days
RBC Osmotic Fragility
Osmotic Fragility, RBC
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Suspected hereditary spherocytic hemolytic anemia.
> or =12 months: 0.50 g/dL NaCl (unincubated): 3-53% hemolysis; 0.60 g/dL NaCl (incubated): 14-74% hemolysis; 0.65 g/dL NaCl (incubated): 4-40% hemolysis; 0.75 g/dL NaCl (incubated): 1-11% hemolysis. Reference values have not been established for patients who are <12 months of age.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimens must be received by performing laboratory within 72 hours of collection. Collect specimen in a lavender top tube. Also collect a normal control specimen in a lavender top tube from an unrelated, non-smoking individual at the same time that the patient is drawn (label "normal control"). Refrigerate both intact specimens; do not transfer blood to other tubes.