Days Set Up
Monday - Friday
Analytic Time

3 - 4 weeks

Soft Order Code

Test Updated:


OncoSeq Germline Analysis
Exome Sequencing

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Exome Sequencing

Test Usage

The OncoSeq assay is designed to identify non-synonymous somatic mutations in a panel of 1700+ genes with suggestive links to cancer by comparing tumor vs a matched normal control.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements


TUMOR: Fresh frozen specimens are preferred for OncoSeq testing. However, if frozen tissue is not available, a formalin-fixed paraffin block containing greater than 40% tumor (minimum 20%) will be accepted. Send FFPE Block from the most recent surgery or biopsy, containing the most amount of tumor along with H&E stained section of the same block.
NORMAL CONTROL: Collect blood by venipuncture in the following order: two 5 mL SST tubes and one Cell-Free DNA BCT (Streck) tube. Gently invert all tubes 8-10 times. Store refrigerated and ship with cold pack. Blood specimens must be received within 24 hours of collection. Blood is the preferred specimen for Normal Control. However, if blood specimens are not available, saliva may be used. Collect specimen according to the instructions included with the collection kit.

Minimum Volume

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.