Days Set Up
Monday - Saturday
Analytic Time

2 - 4 days

MiChart Code
Oligoclonal Banding, CSF (Mayo)
Soft Order Code

Test Updated:


CSF Gamma Globulin Banding
Electrophoresis, CSF
Multiple Sclerosis
Multiple Sclerosis (MS)
O Bands
Protein Electrophoresis, CSF
MS Profile

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Isoelectric Focusing (IEF) with IgG Immunoblot Detection

Test Usage
Reference Range

CSF Olig Bands Interpretation: <4 bands. A finding of 4 or more cerebrospinal fluid (CSF)-specific bands (i.e., bands that are present in CSF but are absent in serum) is consistent with multiple sclerosis. The presence of oligoclonal band is unrelated to disease activity.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Both blood and CSF samples are required. Specimens may be collected within 1 week of each other.

Collection Offsite

Collect both blood and CSF; specimens must be collected within 1 week of each other. Collect blood in an SST tube and aliquot serum into a plastic vial. Refrigerate serum and CSF specimens.

Yellow Top Tube
Normal Volume
0.5 mL serum AND 0.5 mL CSF
Minimum Volume
0.4 mL serum AND 0.4 mL CSF

Billing Information

CPT Code
83916 x2
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.