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Marker of myocardial injury. Troponin I is one of three proteins of the troponin complex that regulates the calcium mediated interaction of actin and myosin. Troponin I demonstrates slightly better cardiac specificity than does CK-MB. Serum levels of troponin I begin to rise 4 to 6 hours after an acute myocardial infarction, with peak concentrations being reached in approximately 12-18 hours after infarction. Unlike other cardiac markers (CKMB, Myoglobin), Troponin I levels remain elevated in plasma for several days before returning to normal. Troponin I may be elevated in a number of cardiac conditions other than AMI, including unstable angina.
< 0.30 ng/mL
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect specimen in a green top tube. Centrifuge, aliquot plasma into a plastic vial and refrigerate.