DNPH spot test
To determine urine ketoacid excretion in MSUD (maple syrup urine disease) patients. Test is also positive in patients with PKU (phenylketonuria).
Interpretive report provided.
Patients excreting material including low solubility drugs and x-ray contrast dye may yield a false positive result. Ketotic patients will also test positive. Positive results in previously undiagnosed patients should be confirmed by Urine Organic Acids testing. Plasma amino acid testing is required to confirm a diagnosis of MSUD. Dilute urine may show a false negative result.
2 - 5 days
- Alpha-Keto Acids
- Urine Ketoacids, DNPH
- DNPH assay for alpha ketoacids
Please notify MLabs Client Services Center to schedule testing prior to collecting specimen. Collect random urine specimen and freeze. Freeze each specimen immediately after collection if multiple collections are needed to reach the minimum volume. Include the patient's family history, clinical condition (asymptomatic or acute), diet, and a list of current medications with the test requisition.
Schedule with laboratory prior to collection.
Refrigerate and page 0603 for pick-up
(F)-frozen if transportation requires more than 1.5 hours.