Analytic Time

7 days

MiChart Code
Anti-NXP2
Soft Order Code
RNXP2

Test Updated:

Synonyms

Anti-NXP2
NXP-2 (P140)

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All specimens should be accompanied by a requisition.

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Test Overview

Test Methodology

EIA

Test Usage

Anti-NXP-2 antibodies are present in 1.6-30% of adult DM and 18-25% of JDM. In JDM they are associated with cutaneous calcinosis cutis. In adult DM they are significantly associated with the presence of cancer (cancer was found in 13.6% of Anti-NXP-2 positive DM patients). Anti-MDA5 antibodies are present in 7-35% of adult DM. Features consist of absent or mild muscle symptoms (CADM); associated with rapidly progressive ILD; specific mucocutaneous features of skin ulcerations and papules; higher risk of oral ulcerations and arthritis.

Reference Range
 

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection

Collect specimen in an SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Yellow Top Tube
Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum

Billing Information

CPT Code
83520
Pro Fee Code
 
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.

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