Days Set Up
Tuesday, Thursday
Analytic Time

2 - 6 days

MiChart Code
NTx Serum (Sendout)
Soft Order Code

Test Updated:


N-Telopeptides, Serum
Pyrrolinks-D, Serum
Crosslinked N-telopeptide of Type 1 Collagen, Serum
Type I Collagen (NTX), Serum
Collagen Crosslinks, Serum
N-Telopeptide, Cross-Linked, Serum

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

Visit our provider FAQ and learn about common questions to ordering tests.

Test Overview

Test Methodology


Test Usage

This test is used for monitoring effectiveness of antiresorptive therapy in patients treated for osteoporosis or other metabolic bone disorders or as an adjunct in the diagnosis of medical conditions associated with increased bone turnover.

Reference Range

All units are reported in nmol Bone Collagen Equivalents (BCE). Adult Male: 5.4-24.2 nmol BCE; Adult Female, Premenopausal: 6.2-19.0 nmol BCE.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in a red top or SST tube from a fasting patient (preferred).

Collection Offsite

Collect specimen in a red top or SST tube from a fasting patient (preferred). Centrifuge, aliquot serum into a plastic vial and freeze.

Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.1 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.