Analytic Time

5 - 6 weeks

Soft Order Code

Test Updated:


Neurofibromatosis Type 2 (NF2) Gene Sequencing

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

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MLabs provides all the supplies necessary for the collection of specimens.

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Test Overview

Test Methodology

Direct test using an RNA/cDNA-based direct sequencing of the entire coding region and MLPA analysis to detect copy number changes. Copy number changes are confirmed by long range RT-PCR, quantitative PCR and/or aCGH.

Test Usage

Confirmatory diagnostic testing; Testing in an affected patient to prepare for predictive testing and early detection of at-risk relatives for management reasons; Predictive testing for early detection of at-risk individuals for management reasons; Testing in an affected patient to prepare for prenatal diagnosis and/or pre implantation diagnosis.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect sufficient lavender top tubes. Send intact specimen at room temperature. Specimens are accepted by MLabs Monday through Thursday only and must be received by performing laboratory within 60 hours of collection (specimen must be received by MLabs by 6:00 pm). Specimen must be accompanied by NF2 laboratory request form, NF2 informed consent form, and phenotypic checklist form available from MLabs.

Lavender Top Tube
Normal Volume
10 mL EDTA whole blood
Minimum Volume
3 mL EDTA whole blood

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.