Days Set Up
Daily
Analytic Time

24 hours

MiChart Code
NGAL
Soft Order Code
NGAL

Test Updated:

Synonyms
 

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All specimens should be accompanied by a requisition.

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Test Overview

Test Methodology

Particle enhanced immunoturbidimetric Immunoassay

Test Usage

Acute Kidney injury (AKI) is a common and serious condition in critically ill patients. AKI is associated with poorer overall outcomes, including increased mortality, prolonged length of stay, and increased risk of progression to chronic kidney disease. Neutrophil gelatinase-associated lipocalin (NGAL) is an emerging biomarker for the early detection of AKI. Studies have shown NGAL to be a highly induced protein in the kidney after ischemic or nephrotoxic injury. When added to currently used criteria of serum creatinine and urine output, NGAL can help to identify those at risk of progressing to worsening AKI.
Elevations of urine NGAL are not entirely kidney specific, and can also be observed with infections, inflammation, and in some cancer patients. Urine levels greater than 300 ng/ml yield a higher specificity

Reference Range

NGAL level Interpretation
<149 ng/ml AKI risk: Low
150 - 300 ng/ml AKI risk: Moderate
>300 ng/ml AKI risk: High

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Random Urine

Collection Offsite

Collect a random urine specimen. Refrigerate for up to 3 days.

Normal Volume
Greater than 3 mL random urine
Minimum Volume
1 mL random urine

Billing Information

CPT Code
83520
Pro Fee Code
 
LOINC
74099-3

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.