Days Set Up
Tuesday, Thursday
Analytic Time

4 - 10 days

MiChart Code
Histamine, Random Urine (Mayo NMHR)
Soft Order Code

Test Updated:


N-Methylhistamine, Urine
NMHDR - Collection Duration
NMHTV - Urine Volume

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)

Test Usage

Assist in screening for and monitoring mastocytosis and disorders of systemic mast cell activation.

Reference Range

Age 0-5 yrs: 120 - 510 mcg/g creatinine; age 6-16 yrs: 70 - 330 mcg/g creatinine; age >16 yrs: 30 - 200 mcg/g creatinine.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

Collect random urine. Transfer urine aliquot to a plastic container and refrigerate. Patients should not consume histamine - rich foods (e.g., cheese, chicken liver, eggplant, sauerkraut, sirloin steak, spinach, tomatoes, wine, or yogurt) for 24 hours prior to start of or during urine collection. Indicate if patient is taking an antihistamine.

Normal Volume
5 ml urine
Minimum Volume
3 ml urine

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.