Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Assist in screening for and monitoring mastocytosis and disorders of systemic mast cell activation.
Age 0-5 yrs: 120 - 510 mcg/g creatinine; age 6-16 yrs: 70 - 330 mcg/g creatinine; age >16 yrs: 30 - 200 mcg/g creatinine.
Individuals who are taking monoamine oxidase inhibitors (MAOIs) or aminoguanidine will have increased levels of NMH. Results from patients on MAOIs are uninterpretable.
4 - 10 days
- HISTAMINE RANDOM URINE
- N-Methylhistamine, Urine
- NMHDR - Collection Duration
- NMHTV - Urine Volume
Collect random urine. Transfer urine aliquot to a plastic container and refrigerate. Patients should not consume histamine - rich foods (e.g., cheese, chicken liver, eggplant, sauerkraut, sirloin steak, spinach, tomatoes, wine, or yogurt) for 24 hours prior to start of or during urine collection. Indicate if patient is taking an antihistamine.
Test sent to Mayo Medical Laboratories.