Days Set Up
Analytic Time

2 - 5 days

Soft Order Code

Test Updated:


CSF, Myelin Basic Protein
Multiple Sclerosis (MS)
Spinal Fluid, Myelin Basic Protein

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Test Overview

Test Methodology

Chemiluminescent Immunoassay

Test Usage

The most common indication for ordering the MBP test is in the differential diagnosis of Multiple Sclerosis (MS). Elevated concentrations of MBP in the CSF is only an indication of demyelination, which can occur in clinical contexts other than MS. Therefore, elevated concentration of MBP in the CSF should not be considered as a diagnostic marker for MS. Recent revisions to the diagnostic criteria for MS include CSF oligoclonal IgG bands and/or increased IgG index, but not MBP measurements.

Reference Range

0.0 - 5.50 ng/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Place CSF in a clean plastic screw capped tube or container.

Collection Offsite

Place CSF in a clean plastic screw capped tube or container and freeze.

Normal Volume
1 mL CSF
Minimum Volume
0.3 mL CSF

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.